This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates several residues of the S6 ribosomal protein. The kinase activity of this protein leads to an increase in protein synthesis and cell proliferation. Amplification of the region of DNA encoding this gene and overexpression of this kinase are seen in some breast cancer cell lines. Alternate translational start sites have been described and alternate transcriptional splice variants have been observed but have not been thoroughly characterized.
70 kDa ribosomal protein S6 kinase 1; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70(S6K)-alpha PS6K S6K1 STK14A; P70S6K1; Ribosomal protein S6 kinase beta-1; Ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; S6K-beta-1; serine/threonine kinase 14 alpha; Serine/threonine-protein kinase 14A
Cat # 16300425
100 µL
Cat # 11527130
100 µL
Cat # 13422717
100 µL
Cat # 16548931
100 µL
Cat # 16363485
100 µL
Cat # 15357094
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Cat # 15377284
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Cat # 13477047
500 µL
Cat # 15348120
100 µg
Cat # 11346063
100 µg
Cat # 16388044
100 µL
Cat # 11501643
100 µg
Cat # 11515111
100 µL
Cat # 16314614
100 µL
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